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I am not taking Herceptin as yet. However, since Herceptin can have adverse cardiac effects and the long-term effects are not well known yet, based on your description I think you see your doctor and consider requesting either an echo or a MUGA scan. I don't know how old your and your heart are, but continued swollen ankles and heaviness of the chest with or without a history of Herceptin should be investigated promptly.
AlaskaAngel
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