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Sheila, I'm on the lowest dose; 500mg am and 500mg. pm. The plan was to increase slowly, but I showed immediate response and so we've just continued on the same low dose. I too have stubborn neck and collarbone nodes, and they're finally shrinking on this combo: Xeloda/Navelbine(also low dose)/Herceptin. I see my onc today, will let you know if anything changes. Good luck with Xeloda, I've found it very easy, my only problem has been low blood counts but that's been an issue all along with Navelbine, so I don't think the Xeloda is a huge factor there, although my nurses said it CAN lower your counts although not usually as much as other chemos.
<3 Lolly
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