HER2 Support Group Forums - View Single Post - Interesting article/clinical trial/preventing bone mets stage I-III

Barbara2 · 03-23-2006, 03:42 PM

Clodronate was used in the clinical trial that was made reference to above, but why not ask for any of the other types of bisphosphonates such as Fosamax or Actonel?

Aredia and Zometa ( both intravenous) are used in metastatic breast cancer as was Clodronate.

"The researchers concluded that these results add to findings indicating that the use of bisphosphonates such as Clodronate in the treatment of early breast cancer appears to resist the risk of bone metastasis and may affect survival in some patients. Further study is necessary to determine how to incorporate bisphosphonates into the treatment of earlier stages of cancer."

Barbara

03-23-2006, 03:42 PM	#9
Barbara2 Senior Member Join Date: Sep 2005 Location: South Dakota. Posts: 621	Why not use another type of bisphosphonate that can be ordered by your onc? Clodronate was used in the clinical trial that was made reference to above, but why not ask for any of the other types of bisphosphonates such as Fosamax or Actonel? Aredia and Zometa ( both intravenous) are used in metastatic breast cancer as was Clodronate. "The researchers concluded that these results add to findings indicating that the use of bisphosphonates such as Clodronate in the treatment of early breast cancer appears to resist the risk of bone metastasis and may affect survival in some patients. Further study is necessary to determine how to incorporate bisphosphonates into the treatment of earlier stages of cancer." Barbara