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Lani
I am reading the complete article and think you may have misinterpreted the reference to "parenchymal" brain disease"--I think they are contrasting that to "leptomeningeal disease" ie, the problem is within the substance of the brain itself, rather than the lining of the brain.
I am unable to copy and paste from the article, as I have it as a pdf and have technical problems sending it as an email...oh well!
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