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I am taking 1,500mgs of Xeloxa, twice daily, and I am a small person. I really wish I could convince my Oncologist that less is more. I am 4 days into my cycle of 14 and already my hands are getting sore and red. I've had blisters all over my hands and feet with this stuff and had to get off for 2 weeks. I LOVE playing tennis, it was my stress relief and now I can't play because it agrivates my hands. I really want to exercise but any friction messes my hands and feet up..all I can do is swim. Do you have any link to articles about the "smaller dose" working as well. I'd love to give my Oncologist written support of this, he is very open minded and would listen. Although, I had such good results on my 6 week scan, I think he doesn't want to change anything. I may just have to rough it for another few months and hope I get NED...sherryg683
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