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I really don't understand why more onc's don't give the taxotere weekly. The side effects are so much less when you take it weekly and the few reports I have seen suggests that it is just as effective as the 3week regime. I think the problem is similar to the too high xeloda issue...the original studies were done with very high dose so the standard of care was to begin people at the 4,000mg/day level.....slowly the doc's are figuring out that that is too high and that significantly lower doses work just as well with less side effects.
It's not very exciting to fund new trials for an already exisiting drug but at lower doses so it takes a long time to change the standard of care and get the word out.
kk1
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