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Old 03-07-2006, 12:21 PM   #1
mom22girlz
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Join Date: Mar 2006
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Does Her2 + status nearly guarantee chemo?

I have been diagnosed with Stage 1 breast cancer. At first thought I would just have radiation, but now the Dr. indicates a possible need for more. will find out on March 14. I got the impression it was because of my her+ status. I am 47 and premenopausal. does this perhaps mean chemo? I was also a bit confused by my pathology report. Any one who can decipher?


The breast tissue aggregates to 4 cm in greatest dimension. Multiple sections of breast biopsy show extensive ductal carcinoma in situ (cribform, micropapillary and solid type) with high grade cytology. Blocks (7 and 9) show foci of microinvasive carcinoma with surrounding stromal reaction. Sections of the surgical resection margin show no evidence of malignancy.

ER 2+
PR 2+
Her2 2+
FISH results 25 cells examined her-2/neu signals to chromosomes 17 signals calculated. Ratio was 6.41, indicating amplification of this gene.

Thanks. S
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