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Old 02-24-2006, 07:51 PM   #12
Lani
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combining treatments of more than one ERBB receptor

I attended a lecture given a representative of the research department of Genentech and they reported that the combinations of Tarceva/Iressa and Herceptin in clinical trials so far had not shown the synergy they had hoped for(and expected due to the preclinical results). Hopes are higher for the Lapatinib-Herceptin combination. The best article on the matter I have found so far is the following. Please let me know if the link doesn't work (I am a novice at this)

mct.aacrjournals.org/cgi/reprint/3/10/1335
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