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Re the evolutionary theory.
I cannot comment on the impact of declining or increasing eostrogen, but I have seen articles suggesting that cancers are in part a reflection of an evolutionary response, a triggering of elemental cells in reponse to environmental stress (of all sorts including diet), and I would guess oestrogen is in there somewhere. The more I read on oestrogen the more complex it appears given the bodies ability to produce it in different ways at different sites, to store it etc. I think the trials / suggestions that in certain limited circumstances that eostrogen can work against BC, might indicate it is all a great deal more complex than we yet realise, and todays absolute views on eostrogen exclusion might become rather less absolute in the future - as to the relative merits of your discussion I simply have not read do not know enough to comment specifically.
My personal strictly amateur guess at a significant trigger is the huge excess of omega six intake, over historic levels compunded by low omega threes, trans fats, and exclusion of small amounts of traditional sources such as dairy. It is a clearly evident trend. The impact of grossly stoking the omega six emergency repair inflamatory pathways are also evident in many other related diseases, coronary, diabetes, arthritis. Fats are truly fundamental to life.
That is not to say it expalins all or is the only factor, but my hunch is it is a magor one.
RB
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