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Lolly · 02-01-2006, 11:16 AM

Ladies, I've had my LVEF drop from a high of 68% when I started Herceptin in 2001 to my last reading of 49% a few months ago. It hovered in the mid 50's for most of that time, just recently has dropped and as I'm having no symptoms, and my onc says he's not worried yet even though less than 50% is considered sub-normal.

I've taken Co-Q10 regularly in the past to improve my ejection fraction, as much as 300mg daily, but since I'm now on chemo I only take 100mg as the anti-oxidant effect is counter productive to chemo. Once I'm done with this round of chemo, I plan to up my dose of Co-Q10 again and expect my LVEF to improve.

If you Google CoQ-10 you'll find many references to it's documented ability to repair heart function specifically related to congestive heart disease which is why many of us on this site who are on Herceptin therapy use CoQ-10 as a supportive therapy.

<3 Lolly

P.S. IMPORTANT REMINDER: Too much CoQ-10 while ON CHEMO is not a good thing as the strong anti-oxidant properties can be counter productive to killing cancer cells by actually helping them REPAIR the damage done by chemo. Obviously not what we want, so be careful of the dosage while on chemo. Usually 100mg as a supportive dose to maintain LVEF is what has been recommended by others on this site who have done much research on this subject. After chemo, when on just Herceptin, up to 300mg is considered safe by those here and has been shown to be therapeudic in studies.

02-01-2006, 11:16 AM	#10
Lolly Senior Member Join Date: Aug 2001 Location: Oregon Posts: 1,756	Ladies, I've had my LVEF drop from a high of 68% when I started Herceptin in 2001 to my last reading of 49% a few months ago. It hovered in the mid 50's for most of that time, just recently has dropped and as I'm having no symptoms, and my onc says he's not worried yet even though less than 50% is considered sub-normal. I've taken Co-Q10 regularly in the past to improve my ejection fraction, as much as 300mg daily, but since I'm now on chemo I only take 100mg as the anti-oxidant effect is counter productive to chemo. Once I'm done with this round of chemo, I plan to up my dose of Co-Q10 again and expect my LVEF to improve. If you Google CoQ-10 you'll find many references to it's documented ability to repair heart function specifically related to congestive heart disease which is why many of us on this site who are on Herceptin therapy use CoQ-10 as a supportive therapy. <3 Lolly P.S. IMPORTANT REMINDER: Too much CoQ-10 while ON CHEMO is not a good thing as the strong anti-oxidant properties can be counter productive to killing cancer cells by actually helping them REPAIR the damage done by chemo. Obviously not what we want, so be careful of the dosage while on chemo. Usually 100mg as a supportive dose to maintain LVEF is what has been recommended by others on this site who have done much research on this subject. After chemo, when on just Herceptin, up to 300mg is considered safe by those here and has been shown to be therapeudic in studies. Last edited by Lolly; 02-01-2006 at 01:02 PM..