[julierene]

I am also on the combo. I am 6 weeks into it. I get a break after 3. I haven't lost hardly any hair either. I get some constipation, sleeplessness, and fatigue (go figure), and acne. I go to bed and toss and turn for hours while tired as can be. I have been experimenting with the sleep aids to try and get the right amount for me. I think I can blame some joint pain on it too. I'm only 30 years old, but I have bone and liver mets. The bone mets aren't in the joints that I'm having problems with though. So I hope it's the treatment drugs. But knees and ankles and shoulders all pop like rice krispies now.

I think I am having necrosis pain from shrinking tumors. My cancer symptoms before diagnosis have become better, but I ache in the tumor locations the next day up to several days after the treatment. Then I get better right before I go in again.