HER2 Support Group Forums - View Single Post - finally, someone tells the HER2 survival story the way it is:

al from Canada · 01-29-2006, 05:00 PM

What we suspected all along is confirmed for the first time I'm aware of in print:

"These data suggest that trastuzumab radically changes the natural history of HER2-positive metastatic breast cancer. While women with HER2-positive tumors have historically been thought to have a worse prognosis, the advent of trastuzumab means that they appear to do far better in response to chemotherapy than do patients with HER2-negative tumors, exhibiting higher rates of response, longer durations of treatment, and improved overall survival. Thus, HER2-negative and HER2-positive tumors remain clinically distinct, and it is not fair to say that HER2-negative outcomes are equivalent to HER2-positive outcomes in patients also receiving trastuzumab."

For those who want to read the whole article:
http://www.medscape.com/viewarticle/466393

Finally, we're out of the dungeon; kind of like the tortoise and the rabbit wouldn't you say?

Regards,
Al

01-29-2006, 05:00 PM	#1
al from Canada Senior Member Join Date: Jul 2005 Location: Ontario, Canada Posts: 722	finally, someone tells the HER2 survival story the way it is: What we suspected all along is confirmed for the first time I'm aware of in print: "These data suggest that trastuzumab radically changes the natural history of HER2-positive metastatic breast cancer. While women with HER2-positive tumors have historically been thought to have a worse prognosis, the advent of trastuzumab means that they appear to do far better in response to chemotherapy than do patients with HER2-negative tumors, exhibiting higher rates of response, longer durations of treatment, and improved overall survival. Thus, HER2-negative and HER2-positive tumors remain clinically distinct, and it is not fair to say that HER2-negative outcomes are equivalent to HER2-positive outcomes in patients also receiving trastuzumab." For those who want to read the whole article: http://www.medscape.com/viewarticle/466393 Finally, we're out of the dungeon; kind of like the tortoise and the rabbit wouldn't you say? Regards, Al __________________ Primary care-giver to and advocate for Linda, who passed away April 27, 2006.