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al from Canada · 01-23-2006, 04:09 PM

Dear Terry,

My very unprofessional opinion is that if your tumor was HER2 AND you've already had a reoccurance AND we also know that HER2 over-expression is associated with hormone treatment resistance AND you are currently not taking herceptin, I would be getting a little nervous and be thinking about changing oncs. Just make sure you are at least ICH3+ or IHC2+ and FISH 2+. anything less and you may not require it anyway.

Good luck,
Al

01-23-2006, 04:09 PM	#2
al from Canada Senior Member Join Date: Jul 2005 Location: Ontario, Canada Posts: 722	once HER2, always HER2?? Dear Terry, My very unprofessional opinion is that if your tumor was HER2 AND you've already had a reoccurance AND we also know that HER2 over-expression is associated with hormone treatment resistance AND you are currently not taking herceptin, I would be getting a little nervous and be thinking about changing oncs. Just make sure you are at least ICH3+ or IHC2+ and FISH 2+. anything less and you may not require it anyway. Good luck, Al __________________ Primary care-giver to and advocate for Linda, who passed away April 27, 2006.