HER2 Support Group Forums - View Single Post - Mechanisms of estrogen in promoting cell death in breast cancer discovered

01-15-2006, 05:58 PM

this study was done in MCF7 cells which were not transfected with her2neu

Thus these findings should be interpreted as being in vitro, preclinical and in a totally different type of breast cancer which may or may not utilize the same pathways as estrogen positive her2neu breast cancer.

01-15-2006, 05:58 PM	#3
LANI Guest Posts: n/a	just a word of warning--be careful in interpreting studies done on her2-bc cell line this study was done in MCF7 cells which were not transfected with her2neu Thus these findings should be interpreted as being in vitro, preclinical and in a totally different type of breast cancer which may or may not utilize the same pathways as estrogen positive her2neu breast cancer.