Good question
I tend to go with Lisa in that you should try and find a way if possible to take Herceptin and just let a doc write you off on that very useful drug.
When I take my 3-week dose over 45 minutes I feel just fine, although never had a real problem with 1/2 hour infusion.
Seems I recall someone who had to get it over a 2-hour period so she could take it.
If you are ER positive the estrogen suppressor should work to slow down your tumors that feed on this hormone. It does have efficacy.
Stay with it and talk to the folks at Genentech yourself.
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