HER2 Support Group Forums - View Single Post - Does Herceptin Reverse The Estrogen Receptor?????

Becky · 01-06-2006, 04:37 PM

Your status should should not change if you are ER+PR+ (or neg for PR) if you are also taking a hormonal at the same time as Herceptin (and blocking both receptors simultaneously).

I have read that one can change from negative to positive, both in regard to Her 2 status or hormonal status. I think the change may be "provoked" if you are on the edge to begin with (ie: tested as Her 2 +2 or +1) or so slightly hormone positive that you are considered negative (for example, I am less than 5% PR positive and I am told that it is considered negative (but I am 50% ER positive)).

Becky

01-06-2006, 04:37 PM	#5
Becky Senior Member Join Date: Sep 2005 Location: Stockton, NJ Posts: 4,179	Your status should should not change if you are ER+PR+ (or neg for PR) if you are also taking a hormonal at the same time as Herceptin (and blocking both receptors simultaneously). I have read that one can change from negative to positive, both in regard to Her 2 status or hormonal status. I think the change may be "provoked" if you are on the edge to begin with (ie: tested as Her 2 +2 or +1) or so slightly hormone positive that you are considered negative (for example, I am less than 5% PR positive and I am told that it is considered negative (but I am 50% ER positive)). Becky