HER2 Support Group Forums - View Single Post - Does Herceptin Reverse The Estrogen Receptor?????

suem · 01-06-2006, 03:52 PM

Robin

I have the downloaded an abstract of an article by Munzone et al in Breast Cancer Research 2006, 8:R4 'Reverting estrogen-receptor-negative phenotype in Her-2-overexpressing advanced breast cancer patients exposed to trastuzumab plus chemotherapy'. It hasn't got a link at the bottom so I can't paste it in. I expect I found it via pub med. This is a very small sample of 10 patients with advanced BC, Her2+ve, ER and PR -ve, who received Herceptin weekly as a monotherapy or combined therapy. 3 of the 10 showed overexpression of er first appearing after 9,12 and 37 weeks.

We are using this to ask for a re-test for my sis who has progressed on herceptin, in case hormonal therapies may become an option for her.

Hope this helps

Sue M

01-06-2006, 03:52 PM	#2
suem Member Join Date: Oct 2005 Posts: 6	Robin I have the downloaded an abstract of an article by Munzone et al in Breast Cancer Research 2006, 8:R4 'Reverting estrogen-receptor-negative phenotype in Her-2-overexpressing advanced breast cancer patients exposed to trastuzumab plus chemotherapy'. It hasn't got a link at the bottom so I can't paste it in. I expect I found it via pub med. This is a very small sample of 10 patients with advanced BC, Her2+ve, ER and PR -ve, who received Herceptin weekly as a monotherapy or combined therapy. 3 of the 10 showed overexpression of er first appearing after 9,12 and 37 weeks. We are using this to ask for a re-test for my sis who has progressed on herceptin, in case hormonal therapies may become an option for her. Hope this helps Sue M