Dear Nicola, (warrior princess and protector of the small molecule invaders)
You are truly a warrior and an explorer! It is from people like yourself that the rest of us will learn and benefit. Trials and there entries are all a matter of timing: the right place with the right prognostic / diagnosic information required and time; it takes courage to make the time for these trials.
Linda and I wish you the utmost success with your treatment and thankyou for pushing the envelope. Who knows, 10 myears from now they will be singing songs of praise to the "first 20" as they were at SABCS and the "first 20".
I think this combination has excellent opportunities for success and I truly believe you have made a smart therapeutic decision. Please pay close attention to the "do not mix" items because they refer to the cytochrome 450 mediated metabolism that was discussed last week. aka grapefruit juice is a no no! as is everything else on the list
Go to this discussion to clarify this interaction:
http://her2support.org/vbulletin/showthread.php?t=21808
Take care and good luck,
Al and Linda