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Snoopy
THAT IS AN EXELLENT INFORMATIVE LINK - IN THE COMPULSORY READING CATEGORY I WOULD SUGGEST.
It brings together all sorts of threads in one place. I have posted a trial earlier on this site which identifies that Tamoxifen may increase tumour growth in some instances as suggested in your link, and have seen the suggestion made elsewhere as well.
A complex subject which deserves greater study given the impact of Tamoxifen both good and bad.
Another thing to consider is that Tamoxifen trials are often against a base of no treatment, and when RT / RT and boost are included the incremental benifit is lower.
There is also the question of trying to find statistics on benifits for long term survival as against regional reoccurence.
Difficult and complex decsions.
RB
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