HER2 Support Group Forums - View Single Post - HER-2 Positve BC Doubles Risk of Brain Metastases

Rozebud · 12-14-2005, 09:55 AM

How long would it be between the time you'd have a met and the time you'd have symptoms? Kristen, I understand what you mean, I am tempted to lie to get them is most mets show up without symptoms, but I feel it's not right to do. What does everyone else think?

As to the stat, I think you take 57% divided by the number of people who have her2 positive cancer (let's say 22.5% for average sake). So 57/22.5 = 2.5x as high of a risk. Meaning over 1/2 of the people in this small study who have brain mets are her2+ but the general b/c population has less than 1/4 that are her2+. Hope that makes sense.

12-14-2005, 09:55 AM	#16
Rozebud Senior Member Join Date: Nov 2004 Location: Olathe, KS Posts: 107	How long would it be between the time you'd have a met and the time you'd have symptoms? Kristen, I understand what you mean, I am tempted to lie to get them is most mets show up without symptoms, but I feel it's not right to do. What does everyone else think? As to the stat, I think you take 57% divided by the number of people who have her2 positive cancer (let's say 22.5% for average sake). So 57/22.5 = 2.5x as high of a risk. Meaning over 1/2 of the people in this small study who have brain mets are her2+ but the general b/c population has less than 1/4 that are her2+. Hope that makes sense. __________________ Rose Dx'd 1/04 at 33, while 33 weeks pregnant Dx: Stage IIIC IDC, ER-, PR+ (23%), Her2=2.7 (IDC)/7.6 (FSH), 2.5cm primary tumor, grade III, 11/18+ nodes (largest 3.8 cm) Treatment: A/C 4, T 4, 1 year of herceptin (BCIRG 006), mastectomy, rads (7 weeks), zoladex (5 years) with tamoxifen (2 years)/aromisin (3 years), bilateral SGAP summer 05 at NOLA Oops, retested tumor and I guess I'm er/pr- after all. Stopped all hormonal tx 10/07. Periods resumed 6/08. Bye bye hot flashes!!!! http://www.edrie.com/kopecky ~VISIT OUR FAMILY!~