This is the same combo I had. I was in a study to give carbo before stage 4. It really whiped me out.Fatigue was bad so I gave myself permission to rest.I was looking foreward to getting my strength back after the A/C because others who were on taxol and herceptin said it would be a piece of cake. They didn't know about the carboplatin thrown in. Constipation is also a big complaint and what I did was take a stool softener daily and keep track of BMs.If it goes a day longer than normal I would eat some prunes (not my favorite) at night and it usually did the trick.Good luck to you and your wife. It is great that she has someone like you watching out for her.
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