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Old 11-25-2005, 05:13 PM   #12
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A component of evening primrose oil

I cannot get access to the article as I have not subscribed.

I think I have seen a summary elsewhere.

Evening Primrose oil is reported as 75% linoleic (omega six) 10% GLA.

GLA is part of the eicosanoid pathway and it is made in the body from Linoleic acid.

It is reported GLA can be converted to Arachidonic Acid AA which among other thing is turned into Cox 2s.

The point is in the body how much GLA is used in lipid or phospholipid form which may be the part that helps in cancer terms as against being turned into something else.

I would suggest caution research and consideration of looking at the overall omega six intake and balancing with omega three etc. It is a question of balancing the likelihood of the possible benifit from GLA against downsides of adding to omega six consumption, and the possiblity GLA is used to make AA.

On the other hand there are suggestions that it is used preferentially in another pathway (series 1)

I have seen a trial on of GLA rats and if I find it I will post a link as it explains the some of the pathways.

Borage oil has a higher level of GLA and lower linoleic and so would possibly be a much better source if chosen as a supplement. Linoleic 39% GLA 24%

Some people are theorised as having difficulty in making GLA from linoleic acid and this is suggested as part of the reson it is effective.

But please do think about trying to get towards an omega three to six balance of one -one which I am much more confident about saying is a must to consider.

The American Cancer Society web site has some information in it. http://www.cancer.org/docroot/ETO/co...p?sitearea=ETO


I hope the above is some help - my head is spaggetti too.

RB
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