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I have been on Arimidex since June. I am Her 2+, ER + but PR (-). Had ovaries removed. At first, I'd have a hot flash every night with sweats but that has gone away. No joint or muscle pain at all. It is like taking nothing. My mom had bc but not HER 2 and is on it (took Tamoxifen for years first as it was the only thing) and she doesn't have any symptoms either. My mom didn't gain any weight on either drug and I haven't gained any weight on Arimidex (never took Tamoxifen).
I take my pill just before bed because my girlfriend said that if you do get hot flashes then they are at night and not during the day (I don't know if this is true but that's why I take it at night).
Love and Peace
Becky
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