[RhondaH]

I was dx 2/1/05 w/ Stage 1, Grade 3, no node, ER/PR-, Her2+ BC. Had partial mastecomy 2/7/05. Finished 6 rounds of dose dense TEC (Taxotere, Epirubicin and Cytoxan) 5/18/05. 33 rads 8/1/05. Began every 3 week Herceptin 8/18/05. Today when I went in for my Herceptin, my nurse asked when my last bloodwork was. I told her the time prior. She then asked me if I had a drink the night before and I told her no. She said my liver enzymes were up so she wanted to do another blood draw prior to giving me my Herceptin. After she did this she said that my body may not be tolerating the Herceptin every 3 weeks. When the tests came back they were as follows:

9/8/05: ALK PHOS 139 (normal 32-122
10/20/05: ALT 64 (normal 12-45)
AST 41 (normal 10-34)
ALK PHOS 175 (normal 32-122)
11/10/05: ALT 45 (normal 12-45...back to normal)
AST 23 (normal 10-34...back to normal)
ALK PHOS 173 (normal 32-122...down 2 points)
GGT 130 (normal 7-40..this was the first time this test was shown and she said the doc she asked said this test could be high if you sneeze)

PLEASE...help ease my mind and tell me what this could mean (other than liver or bone mets).

Rhonda Hoffman