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Lyn, I think there is a difference in the guidelines for Herceptin depending on whether you are stage 4 or not. Stage 4 considers that Herceptin will be a lifetime maintenance drug essentially, but for stages 1-3, the use of Herceptin to prevent mets spread to another organ does not have such clear cut time frame indications yet.
The thinking previously was one year of Herceptin for prevention of mets, but that may be in debate at this time.
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