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Yes, I would want to know what the FISH results would show. My IHC was Her2++, which is "in between" but the FISH was 8.6 which is strongly positive.
I would prefer the original speciman.........
I do know of a lady who was strongly Her2+, but 6 years later the cancer had gone to a muscle, then the lungs, and test results were Her2 negative. That was the first I had ever heard of it changing. She said, yes, her onc said it is possible for the cancer to change.
Would the PTEN test be of help? There has been discussion on this board regarding that test. You could read that for more information.
Blessings....
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