[hope]

Initially at dx I was Her2+++. They did an IHC test on breast tumor tissue. In Feb. 2004 I had a broncoscopy done and they did another IHC test this time on lung tumor tissue and was Her+++. Recently had another broncoscopy done due to some plural effusion on rt. lung and they did another IHC test this time it said I was Her negative. I know about the FISH test but never got one. My onc. dosen't seem to want to give me a FISH test saying that at the 3rd broncoscopy that they might have picked up some more Her negative cells than before but she still thinks I have some postive Her2 cells and continues to give me Herceptin weekly along with Abraxane.

I called the lab who did the last test and they were eager to do a FISH test but they will do it on the last bronc. sample not my original breast biopsy. Should I have a FISH done on the original as well? I haven't got the results yet I heard it takes a while. Also is it possible to switch from Her+++ status to negative? What I think is the lab made an error. Hope