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I was dx Stage IIIB, er/pr- Her2+++ in '99, had the gold standard tx and progressed to Stage IV 6 months after finishing rads. Since I had fairly advanced cancer at primary dx, I probably would have progressed anyway even IF Herceptin had been available to me, but of course I wonder and I have to put in my 2 cents: If you can get it now, do it!!!
Also, regarding the question of whether Herceptin now would cause resistance later when/if needed, I have read reports (somewhere, will try to find them and post later) that when Herceptin has been suspended for a period of time, the cancer cells can become re-sensitized to it and it can be used succesfully again. Hope this is helpful.
<3,
Lolly
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