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I just switched to the every 3 weeks. I had 12 weeklies and this Friday will be my second every 3 weeks.
There was no difference as far as the extremely mild side effects I get (slight headache, tired the next day (but not unduly so) and a runny nose).
Also, like Lolly said, it is nice to not have to be chained to the cancer center every week. I feel that if I travel my non herceptin weeks, I don't have to freak out about getting iced out of Newark airport this winter.
Warm regards
Becky
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