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Mickey I use to go on and off the herceptin depending if I was in or out of chemo. Now, I stay on it because it takes 3 to 4 months for it to work in the body. I was told at New England Tufts that there is no way to know if it is working. It may not prevent a recurrence however, it may slow the cancer down and keep it stable. I would stay on it but that is me. hugs, Sandy
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