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Hi, Julie,
I read the other posts, but I will just tell you what I have noticed. If the ALK Phos is showing a worrisome and continuing upward trend into the 100's, in my experience, this has represented minor bone mets, usually will correlate with just one spot lighting up on the CT...if the number goes into the 250-300, 400 range, it generally means extensive bone mets, provided that the liver enzymes are stable. If you have elevated alk phos and elevated liver enzymes, it is usually liver mets (have had those too). Right now, the liver is quiet but my alk phos is doing exactly what yours is and I am correlating it to pain in my sternum which is where I light up on the bone scan. I think another bone scan would be a good bet, just in case. Also, just remember that just keeping the CA 15.3 below 30 is not always good enough when her-2 is involved. This marker is similar to the CA 27/29 and in order for the serum her-2 levels to be within normal range, the CA 27/29 can not be much higher than 10 to 15...fyi. Look at the whole picture. What are your calcium blood levels...are they increasing as well?? Good luck to you, Gina
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