Jo, I've been researching Xeloda for quite some time. Lots of good input on the bcmets.org site as well.
Currently, the 'new' standard for dosage is to start a patient on 75% of the 'old' standard. And reduce down from there if necessary because of hand/foot or the like.
It has been shown over and over again that people do just as well, response wise, on the lower dosages without the debilitating side effects.
My onc started me on an even lower dose: 1000mg 2x day, for a total of 2000mg a day. I am 5'5" @ 118 lbs. I have seen others on this lower dosage as well.
I'm gonna try to put in a link to how to figure out the dosage of stuff by body surface area... However, I am quite serious about the Xeloda doing just as good a job at the lower amount!!!
http://www.halls.md/body-surface-area/bsa.htm
hugs with love,
pattyz