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08-31-2005, 11:02 AM

Jojo,

I have been on Xeloda and Cytoxan for about 6 months now for skin mets. It seems to be working, as mets have disappeared...but skim mets are tricky business. My dosage regiment is 1st week 500 mg (but not sure here could be 1000 mg) of oral Cytoxan, then 2nd week 3000 mg of Xeloda AND the 500 mg. of Cytoxan, then 3rd week just the 3000 mg. of Xeloda. Then I start the cycle again. This is new according my Onc., but they are seeing positive results with adding the cytoxan, as it is known to cut the blood supply to the cancer cells.

My side effects are as expected, nothing too drastic. Have had diaharea. Usually only during the 3rd week. Hand and Foot syndrome is present, but tolerable. Hair is thinning, but still have most of it...that is from the Cytoxan. My blood work has been fine. Did have low red cell count, but three shots of Aresnap and red cell count has been fine for couple of months. No nausea. Minimal tiredness.

All in all it has been a very tolerable drug for me. Happy to be able to take it at home and not make so many trips to see Onc. Only see her once a month and get my Herceptin then.

Navelbine was the drug that gave me problems (had SEVERE back muscle spasms with every dose). Didn't even control or reduce the skin mets for me. So, everyone can react differently to each chemotherapy, that's for sure.

Cindi.

08-31-2005, 11:02 AM	#6
_Cindi_ Guest Posts: n/a	Jojo, I have been on Xeloda and Cytoxan for about 6 months now for skin mets. It seems to be working, as mets have disappeared...but skim mets are tricky business. My dosage regiment is 1st week 500 mg (but not sure here could be 1000 mg) of oral Cytoxan, then 2nd week 3000 mg of Xeloda AND the 500 mg. of Cytoxan, then 3rd week just the 3000 mg. of Xeloda. Then I start the cycle again. This is new according my Onc., but they are seeing positive results with adding the cytoxan, as it is known to cut the blood supply to the cancer cells. My side effects are as expected, nothing too drastic. Have had diaharea. Usually only during the 3rd week. Hand and Foot syndrome is present, but tolerable. Hair is thinning, but still have most of it...that is from the Cytoxan. My blood work has been fine. Did have low red cell count, but three shots of Aresnap and red cell count has been fine for couple of months. No nausea. Minimal tiredness. All in all it has been a very tolerable drug for me. Happy to be able to take it at home and not make so many trips to see Onc. Only see her once a month and get my Herceptin then. Navelbine was the drug that gave me problems (had SEVERE back muscle spasms with every dose). Didn't even control or reduce the skin mets for me. So, everyone can react differently to each chemotherapy, that's for sure. Cindi.