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Sue,
Yes, go ahead with the tests...better to know a dark and terrible truth than not to know it...yet, judging from the numbers you posted, especially the GGT (mine is elevated always as well), I would suspect it is not brain mets but liver mets...like StephN, I completed all the slash/burn blah blah and even though I was NED at the end of it all, 5 months later, I had mets to the liver, both lobes...lesions as large as 50 cent pieces, quarters, nickles and dimes and liver enzymes OFF THE CHART. I felt lousy...fortunately, only 5 doses of Herceptin WAY back then...1999, brought my tumor markers and liver enzymes back into control and my leisions regressed to practically nothing. Just take a deep breath and try not to worry. Also, just in case, have your blood checked for the ulcer causing H. pylori bacteria...it also tends to raise the GGT high like that and can be cured with antibiotics... What most people don't realize is that besides being an indication of cancer, the actual most common reason for liver enzyme elevation (provided you are not a drinker...as alcohol consumption causes the GGT to be out of whack also, that is why Insurance companies test your blood for it and if you say you drink no alcohol but the GGT is positive they will think you lied on the form...blah, blah) as I was trying to say, the actual most common reason for the liver enzymes to be elevated...esp. the ALT is INFECTION, usually low grade and HARD to detect..somewhere in the DIGESTIVE tract...something WE who are HER-2 positive SHOULD ALL KEEP in check.... Also, if your ALP elevates, but not the liver enzymes, that is usually indicative of bone mets...just so you know. If the ALP and the liver enzymes elevate BE VERY CAREFUL as in practice, this usually indicates pancreatic mets. This her-2 stuff is NOT for the faint of heart...smile. Sorry you have had to join us on this site, but glad you did. Take care, Gina
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