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Christine MH,
Thank you. Your post was interesting as NEITHER would apply to me so, I guess this is another reason why it is hard to make comparissons. Also, I am a firm believer that the persons age, general health, stress level, positive/ negative attitude, stongly vs. weakly Her2, faith, diet and exercise etc. ALL play a factor in their recovery/risk of recurrence.
". In the U.S. trials, herceptin after three weekly AC->taxol reduced recurrence by 13% over AC->taxol whereas adding herceptin to the taxol part slightly more than halved recurrence over AC->taxol. There were hardly any node-negative women in these trials." ***I had 6 dose dense TEC and am node negative (my doctor originally had not planned to give me Herceptin, but must have changed his mind after the news***
"1. Most of the women in the HERA trial just got an anthracycline. For the women who got a taxane in the HERA trial, the reduction in risk of recurrence was 23%, whereas for women who just got an anthracycline, it was much, much larger (I think 67% maybe). So, looking at the two studies it could be that the true benefit of herceptin after an anthracycline + taxane combo would be somewhere between 13% and 23%." ***And I had 6 Taxatere, Epirubicin and Cytoxan combined and dose dense***
2. One third of the women on the HERA trial were node-negative. ***Which I am***
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