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From the first dose of Herceptin over 3.5 years ago with my chemos for mets, I was NEVER given a Benadryl. Only got that with my Taxotere for 4 rounds before the mets.
When I went off the weekly doses of chemo and Hercpetin and got the loading dose for the 3-weekly I was not even offered anything like Benadryl or Tylenol. This does not seem to be the norm at my cancer center and I know a few other women on long term Herceptin as I am who do not get any pre-meds.
Maybe the pre-meds are part of a trial protocal??
But, I do not think the reason would be that Benadryl would actually interfere with the work of Herceptin. That is a new one on me as well!
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