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08-12-2005, 06:27 PM

Patrice,

I know you've had a lot of advice already, but I'd feel guilty if I didn't put my two cents in. With all the positive results surrounding the Herceptin/Taxane combination the paradigm has begun to shift recently to start Her2/pos women with the Herceptin/Taxane combination and then follow with A/C after. The reason why they pick these two therapies is they are not cross resistant. In other words, if the cancer is resistant to the taxane it probably won't be resistant to the A/C and vise versa. My wife followed this sequence and is doing well. Someone mentioned the Herceptin/Navelbine combination which is also very good, but you already gave the Herceptin a shot with the Taxane.

I can't encourage you enough to get second or third opinions, but I think the oncologist is on the money in your situation. You could always follow the A/C with Herceptin afterwards, which your oncologist may already have planned. I am curious as to whether this is neoadjuvant(before surgery chemo) to make the tumor easier to remove from the breast, or if there is no plan to do surgery at all. I would think you would want to have it removed at some point. My wife who is also 34 said she will pray for you.

Best of luck,

SCOTT

08-12-2005, 06:27 PM	#9
_Scott_ Guest Posts: n/a	Patrice, I know you've had a lot of advice already, but I'd feel guilty if I didn't put my two cents in. With all the positive results surrounding the Herceptin/Taxane combination the paradigm has begun to shift recently to start Her2/pos women with the Herceptin/Taxane combination and then follow with A/C after. The reason why they pick these two therapies is they are not cross resistant. In other words, if the cancer is resistant to the taxane it probably won't be resistant to the A/C and vise versa. My wife followed this sequence and is doing well. Someone mentioned the Herceptin/Navelbine combination which is also very good, but you already gave the Herceptin a shot with the Taxane. I can't encourage you enough to get second or third opinions, but I think the oncologist is on the money in your situation. You could always follow the A/C with Herceptin afterwards, which your oncologist may already have planned. I am curious as to whether this is neoadjuvant(before surgery chemo) to make the tumor easier to remove from the breast, or if there is no plan to do surgery at all. I would think you would want to have it removed at some point. My wife who is also 34 said she will pray for you. Best of luck, SCOTT