Hi Susie,
I would strongly recommend you look into the Lapatinib for Metastatic Brain Tumors Clinical Trials at
http://www.cancer.gov/search/ViewClinicalT...&version=Health
There are 3 hospitals participating in Boston, one in Washington DC and one in Chapel Hill NC.
Some in the oncology field are very encouraged by the results they are seeing. It doesn't work for everyone (didn't click for my sister - she ended up with a second craniotomy surgery where 3 separate lesions were removed) but we met a woman for whom the Lapatinib has been working very well to reduce/eliminate lesions. The nice thing about Lapatinib is it's delivered in pill form, and there seem to be few if any side effects.
Are you on Herceptin? That sometimes does a good job at keeping the rest of the body clear, and there's some suspicion that WBR (maybe SRS too) may make the blood/brain barrier more porous, possibly allowing Herceptin to cross into the brain to get at the Her2 cells. The Herceptin molecule is too large to permeate a brain that has not been radiated. For the Lapatinib trial, you must be off Herceptin for at least 2 weeks before starting the trial. My understanding is that Lapatinib works in a similar way to Herceptin, but the Lapatinib(smaller molecule) can cross the blood/brain barrier, prior radiation or not.
Good luck and God's grace be with you - I wish you the very best.
Marianne