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Femara is an aromatase inhibitor (others include Arimidex and Aromosin). They prevent estrogen from being made by the adrenal glands when a woman is postmenopausal (it can't prevent the ovaries from making estrogen if you aren't yet). These drugs are usually given to women who are ER/PR positive. However, I have heard of ER/PR negative women being given aromatase inhibitors or tamoxifen (studies show that tamoxifen may or may not work in HER 2 positive women. It depends on what you want to believe) because there are "theories" that the tissue surrounding the original tumor or "tumors in the making" are ER sensitive (and apparently all tumors or DCISs start ER positive and HER 2 positive then they morph again) and that these drugs MAY help ER/PR negative women too. I would ask your onco his rationale on taking the drug to get his perspective.
Best regards,
Becky
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