HER2 Support Group Forums - View Single Post - Early stage bc "survivors"

05-23-2005, 04:59 AM

Thank you for such good insight Christine. Can you tell us then, where can we get any kind of reliable starting point for using this formula? What I mean is, with treatments in the past five years, what are our chances of survival or reoccurrence, really. On the Mayo Clinic website if you follow it to breast cancer, than to adjuvent therapies then to "your own personal chances" there is a calculator that uses age, lymph node status, tumor grade and hormone status, and then shows 10 year survival without reoccurrence at baseline prognosis, then with different treatments. According to them, an early stage bc survivor has say between an 80-93% chance of being alive in 10 years without reoccurrence, depending on the variables. The most aggressive treatment they base their highest success rate on is ACx4 every 2 weeks + Taxol x4 every two weeks + Tamoxifen. I imagine they will at least soon be updating this to replace Tamoxifen with Femara from what we have seen out of ASCO this time. There is no separate consideration given to HER2, but obviously there were HER2 positive people in the overall 10 year tracking of patients of the general population. Also, if these reports about bone marrow micromets are accurate, they certainly must apply to this overall population as well.

05-23-2005, 04:59 AM	#12
Cheryl Guest Posts: n/a	Thank you for such good insight Christine. Can you tell us then, where can we get any kind of reliable starting point for using this formula? What I mean is, with treatments in the past five years, what are our chances of survival or reoccurrence, really. On the Mayo Clinic website if you follow it to breast cancer, than to adjuvent therapies then to "your own personal chances" there is a calculator that uses age, lymph node status, tumor grade and hormone status, and then shows 10 year survival without reoccurrence at baseline prognosis, then with different treatments. According to them, an early stage bc survivor has say between an 80-93% chance of being alive in 10 years without reoccurrence, depending on the variables. The most aggressive treatment they base their highest success rate on is ACx4 every 2 weeks + Taxol x4 every two weeks + Tamoxifen. I imagine they will at least soon be updating this to replace Tamoxifen with Femara from what we have seen out of ASCO this time. There is no separate consideration given to HER2, but obviously there were HER2 positive people in the overall 10 year tracking of patients of the general population. Also, if these reports about bone marrow micromets are accurate, they certainly must apply to this overall population as well.