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Christine - Most of the multiple node positive women I know recurred later, like between 3 and 5 years. Just had one with 15 nodes recur after 6. Don't know most of the longer one's her2 status as they didn't check it at the time. From what I understand, the highest probability is between 1 and 3 years from dx...but doesn't mean it can't happen. I have 11/18+ nodes. I would take a look at the webcasts from ASCO this week...it might help you with your herceptin decision. The biggest benefit from herceptin was NOT in the first year (per the slides I looked at last night) - it was in years 2 and 3.
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