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Rich, I am also HER2 +++ estrogen+ . I was diagnosed as stage IV with 8/16 nodes positive and one spot on my liver. I had Carboplatin/Taxotere/Herceptin every three weeks for 6 cycles. I then had 33 radiation treatments. I am currently on Letrozole/Herceptin/Lupron since December 2004. I am 37 years old which is why I have the Lupron to shut down my ovaries. I am sceduled to have an oopherectomy in about a month. . My bone density is low in my spine so I figured I'd get rid of the Lupron. I don't know if any of this helped but I just wanted you to know that your mom is not alone. Like that article said, Only 2% of all breast cancer is HER2+++ and estrogen+. Good luck with your mom an dad. Sally
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