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Al,
I recently talked with a hormonal expert in Boston about Exemestane, and he really thinks this will be the A.I . of choice. It continues to be effective in cell lines that have grown resistant to the other two in culture and also has the added benefit of being more bone friendly.
Due to its steroid nature, Exemestane mimicks a testosterone precursor leading to the masculinization of the skeleton and denser bone as seen in men. Years ago they actually prescribed testosterone for breast cancer and it was effective, just that women grew facial hair and deepened voices, so the side effects were deemed unacceptable.
In this case, the side effects of Exemestane are beneficial to bone health, but you won't see any of the secondary side effects as seen with testosterone. The Dr.'s name is Paul Goss for anyone that is interested, and he is in the literature on the internet.
Thanks,
Scott
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