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Dear Celina,
My wife Linda, has been on Navelbine since last April when we discovered liver mets. She has always had serious bone pain as a result of the chemo. Taking neupogen doesn't help because the side effects of it are also bone pain. About 4 months ago we cut her dose down to 3 weeks on, 1 week off, to give her system a greater recovery time from the chemo. This past week she hit a wall. The pain was travelling into her fingers. We are told that this is a result of neurological damage and as a result, she was taken off the Navelbine for at least 4 - 5 weeks after which she will be re-evaluated. She is now on herceptine only. Linda takes hydro-morphone for the bone pain and that seems to do the trick. However, as with any narcotic, constipation is an issue. Things to watch-out for: loss of strength in your ankles and wrists as it is indicative of nerve damage.
All the best,
Al
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