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Marie, I have been on Navelbine/Herceptin twice, for six months each time. Just finished the second regimen, and the reason I went off Navelbine and on to Herceptin maintenance each time was because I had reached NED. If I weren't NED, I wouldn't have wanted to stop the chemo. I think it's basically a case-by-case call, to be made by the patient and doctor.
Personally speaking, if I still had active disease, I would want to remain on a combination therapy, as long as the side effects were tolerable and I had good QOL. Like Lisa says, it's a tough call, but I feel it's YOUR call.
Love, Lolly
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