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Old 11-30-2004, 03:26 PM   #1
Mike
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Hi everyone,

My wife's condition is:

7/12-1.6*1.2 CM local reoccurence (ER+, PR-, HER2+++) with Lung
Mets, 2 spots in both lungs, size from 2-4 MM.
Completed Gemzar/Armidex 3 Cycles (3-on, 1-off)

9/28 - cat scan shows 4 tumors in lungs - ranging in size from 2-6 MM - local
reoccurence is the same size

Started new treament - Gemzar/Herceptin and Fasoldex(monthly), Herceptin weekly, High Dose
Gemzar 1200 Ml every 2 weeks, 1 week off. Had 3 cycles

11/30 - can scan shows 6 tumors in lungs - ranging in size from 2-8 MM - local
reoccurence is the same size

we are waiting to meet with onc later this week to discuss treatment plans

Here are my questions:

-Anybody else with similar experience? Gemzar is not working and not sure about Herceptin
-I think the onc will keep herceptin but switch chemo to navelbine - Comments?
-What about going straight to a taxotere/carboplatin/herceptin combination?
-Is it strange the the local reoccurence has stayed the same size while the nodules
in the lungs keep growing?
-Should we push for biopsy on the lung nodules?

Just some things I am thinking about - thanks very much,

-mike
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