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Hi Sue,
I had 5 doses of Herceptin, 4 of which were along with Taxotere. My Ejection Fraction to begin with was 55%. After taking Herceptin for those 5 times, it went down to 32%!!! I was feeling no symptoms of this and was not unusually tired or weak. Took another one several weeks later and it came back at 43%. They thought there was something wrong with the mugas so they ordered an echo and it came back 45-50%. But, by this time I was already disqualified for my clinical trial and was taken off.
I was very dissappointed about it, but knew I had to quit because of the heart problems. Doc said that 5 doses may have been enough to do the trick. I am Stage 2b and was suppose to be on it for one year. Only had 5 months. So....we'll see.
So, yes it can cause heart problems. Here I thought I was the only one with the problem with Herceptin!
Good Luck to you and hope you are feeling well now.
xoxo,
Shannon
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