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My recurrence occurred also 18 months after original diagnosis. Am er/pr- and her2+3. The good news is those of us with her2+3 are the ones who seem to respond the best to herceptin. I think it is not "if there will be a recurrence, but when". The only thing that may change that is those who have been able to get herceptin with early stage breast cancer. Again, it will be a while before that trial will be able to show if this helps prevent recurrence or just delays it, and if it is safe to give with Adriamycin in particular. Keep in mind there are several vaccine clinical trials going on right now that may really prove to be successful. There is always hope around the corner so it is best to be vigilant and knowledgeable about all options available.
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