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03-02-2004, 11:46 AM

Is anyone on this board faced with this weird set of pathology stats. Grade 1, cribiform, diploid, low S-flow, ER + 95%/ PR + 20%, node negative. Had a large tumor; core biopsied FISH Her2 negative; neoadjuvant and got over a 50% shrinkage. Tumor pathology report came back the same as core biopsy except the Her2/neu was positive at 3+ (IHC test). Am currently beginning radiation. Oncologist believes FISH is right. Will start Tamox after radiation. Wish I knew for sure. For those of you who may have (or had) this kind of conflict, I would like to hear from you.

03-02-2004, 11:46 AM	#1
Marty Guest Posts: n/a	Is anyone on this board faced with this weird set of pathology stats. Grade 1, cribiform, diploid, low S-flow, ER + 95%/ PR + 20%, node negative. Had a large tumor; core biopsied FISH Her2 negative; neoadjuvant and got over a 50% shrinkage. Tumor pathology report came back the same as core biopsy except the Her2/neu was positive at 3+ (IHC test). Am currently beginning radiation. Oncologist believes FISH is right. Will start Tamox after radiation. Wish I knew for sure. For those of you who may have (or had) this kind of conflict, I would like to hear from you.