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Jill,
How wonderful that you've been on Herceptin this long! I'm just starting my 4th year, no problems so far. I remember that some time back there was discussion on the board about possible reactions to the dilutant used to reconstitute Herceptin before infusion. Apparently it contains benzyl alcolhol as a preservative and some have developed a sensitivity to it, so that would be my first guess. If that's the case, saline can be used instead. Good luck, I hope you get to the bottom of this...
Hugs,
Lolly
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